9XZL

Cryo-EM structure of F-box helicase 1 (FBH1) bound to an SCF ubiquitin ligase complex and a 3-way DNA fork (body structure)

Summary for 9XZL

Entry DOI	10.2210/pdb9xzl/pdb
Related	9XZJ 9XZK 9XZM
EMDB information	72361
Descriptor	Cullin-1, F-box DNA helicase 1, S-phase kinase-associated protein 1, ... (7 entities in total)
Functional Keywords	helicase, translocase, fork remodeler, fork reversal, replication fork, dna binding, isomerase-dna complex, isomerase/dna
Biological source	Homo sapiens (human) More
Total number of polymer chains	4
Total formula weight	232533.90
Authors	Mullins, E.A.,Schiltz, C.J.,Eichman, B.F. (deposition date: 2025-08-27, release date: 2026-01-28)
Primary citation	Greer, B.H.,Mendia Garcia, J.,Mullins, E.A.,Peacock, E.M.,Haigh, S.,Schiltz, C.J.,Tsai, M.-S.,Cortez, D.,Moreno-Herrero, F.,Eichman, B.F. F-box helicase 1 reverses replication forks through assembly on the lagging strand template at the fork junction To Be Published,
Experimental method	ELECTRON MICROSCOPY (3 Å)

Structure validation