7JHE
Room Temperature Structure of SARS-CoV-2 Nsp10/Nsp16 Methyltransferase in a Complex with 2'-O-methylated m7GpppA Cap-1 and SAH Determined by Fixed-Target Serial Crystallography
Summary for 7JHE
Entry DOI | 10.2210/pdb7jhe/pdb |
Related | 6W4H 6WJT 6WKQ 6WQ3 6WRZ 6WVN 6XKM |
Descriptor | 2'-O-methyltransferase, Non-structural protein 10, CHLORIDE ION, ... (8 entities in total) |
Functional Keywords | sars cov-2, serial crystallography, methyltransferase, m7gpppa, cap-1, s-adenosylhomocysteine, structural genomics, center for structural genomics of infectious diseases, csgid, viral protein |
Biological source | Severe acute respiratory syndrome coronavirus 2 (2019-nCoV) More |
Total number of polymer chains | 2 |
Total formula weight | 50593.06 |
Authors | Wilamowski, M.,Sherrell, D.A.,Minasov, G.,Kim, Y.,Shuvalova, L.,Lavens, A.,Chard, R.,Rosas-Lemus, M.,Maltseva, N.,Jedrzejczak, R.,Michalska, K.,Satchell, K.J.F.,Joachimiak, A.,Center for Structural Genomics of Infectious Diseases (CSGID) (deposition date: 2020-07-20, release date: 2020-08-26, Last modification date: 2023-10-18) |
Primary citation | Wilamowski, M.,Sherrell, D.A.,Minasov, G.,Kim, Y.,Shuvalova, L.,Lavens, A.,Chard, R.,Maltseva, N.,Jedrzejczak, R.,Rosas-Lemus, M.,Saint, N.,Foster, I.T.,Michalska, K.,Satchell, K.J.F.,Joachimiak, A. 2'-O methylation of RNA cap in SARS-CoV-2 captured by serial crystallography. Proc.Natl.Acad.Sci.USA, 118:-, 2021 Cited by PubMed: 33972410DOI: 10.1073/pnas.2100170118 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.25 Å) |
Structure validation
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