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7JHE

Room Temperature Structure of SARS-CoV-2 Nsp10/Nsp16 Methyltransferase in a Complex with 2'-O-methylated m7GpppA Cap-1 and SAH Determined by Fixed-Target Serial Crystallography

Summary for 7JHE
Entry DOI10.2210/pdb7jhe/pdb
Related6W4H 6WJT 6WKQ 6WQ3 6WRZ 6WVN 6XKM
Descriptor2'-O-methyltransferase, Non-structural protein 10, CHLORIDE ION, ... (8 entities in total)
Functional Keywordssars cov-2, serial crystallography, methyltransferase, m7gpppa, cap-1, s-adenosylhomocysteine, structural genomics, center for structural genomics of infectious diseases, csgid, viral protein
Biological sourceSevere acute respiratory syndrome coronavirus 2 (2019-nCoV)
More
Total number of polymer chains2
Total formula weight50593.06
Authors
Primary citationWilamowski, M.,Sherrell, D.A.,Minasov, G.,Kim, Y.,Shuvalova, L.,Lavens, A.,Chard, R.,Maltseva, N.,Jedrzejczak, R.,Rosas-Lemus, M.,Saint, N.,Foster, I.T.,Michalska, K.,Satchell, K.J.F.,Joachimiak, A.
2'-O methylation of RNA cap in SARS-CoV-2 captured by serial crystallography.
Proc.Natl.Acad.Sci.USA, 118:-, 2021
Cited by
PubMed: 33972410
DOI: 10.1073/pnas.2100170118
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.25 Å)
Structure validation

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