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7JHE

Room Temperature Structure of SARS-CoV-2 Nsp10/Nsp16 Methyltransferase in a Complex with 2'-O-methylated m7GpppA Cap-1 and SAH Determined by Fixed-Target Serial Crystallography

Functional Information from GO Data
ChainGOidnamespacecontents
A0004483molecular_functionmRNA (nucleoside-2'-O-)-methyltransferase activity
B0003723molecular_functionRNA binding
B0008270molecular_functionzinc ion binding
B0019079biological_processviral genome replication
Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues8
DetailsBINDING: BINDING => ECO:0000255|PROSITE-ProRule:PRU01297
ChainResidueDetails
BCYS74
BCYS77
BHIS83
BCYS90
BCYS117
BCYS120
BCYS128
BCYS130

site_idSWS_FT_FI2
Number of Residues1
DetailsSITE: Cleavage; by 3CL-PRO => ECO:0000250|UniProtKB:P0C6V3
ChainResidueDetails
BGLN139

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PDB entries from 2024-11-06

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