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6WVN

Crystal Structure of Nsp16-Nsp10 from SARS-CoV-2 in Complex with 7-methyl-GpppA and S-Adenosylmethionine.

Summary for 6WVN
Entry DOI10.2210/pdb6wvn/pdb
Descriptor2'-O-methyltransferase, Non-structural protein 10, CHLORIDE ION, ... (10 entities in total)
Functional Keywordsstructural genomics, center for structural genomics of infectious diseases, csgid, nsp16, nsp10, complex, viral protein
Biological sourceSevere acute respiratory syndrome coronavirus 2 (2019-nCoV)
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Total number of polymer chains2
Total formula weight52284.83
Authors
Minasov, G.,Shuvalova, L.,Rosas-Lemus, M.,Kiryukhina, O.,Brunzelle, J.S.,Satchell, K.J.F.,Center for Structural Genomics of Infectious Diseases (CSGID) (deposition date: 2020-05-06, release date: 2020-05-13, Last modification date: 2023-10-18)
Primary citationRosas-Lemus, M.,Minasov, G.,Shuvalova, L.,Inniss, N.L.,Kiryukhina, O.,Brunzelle, J.,Satchell, K.J.F.
High-resolution structures of the SARS-CoV-2 2'- O -methyltransferase reveal strategies for structure-based inhibitor design.
Sci.Signal., 13:-, 2020
Cited by
PubMed: 32994211
DOI: 10.1126/scisignal.abe1202
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2 Å)
Structure validation

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