6WVN
Crystal Structure of Nsp16-Nsp10 from SARS-CoV-2 in Complex with 7-methyl-GpppA and S-Adenosylmethionine.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | 2'-O-methyltransferase | polymer | 301 | 33627.5 | 1 | UniProt (P0DTD1) Pfam (PF06460) | Severe acute respiratory syndrome coronavirus 2 (2019-nCoV) | Non-structural protein 16 |
| 2 | B (B) | Non-structural protein 10 | polymer | 142 | 15075.2 | 1 | UniProt (P0DTD1) Pfam (PF09401) | Severe acute respiratory syndrome coronavirus 2 (2019-nCoV) | |
| 3 | C, CA, D, DA, E... (A, B) | CHLORIDE ION | non-polymer | 35.5 | 14 | Chemie (CL) | |||
| 4 | N (A) | S-ADENOSYLMETHIONINE | non-polymer | 398.4 | 1 | Chemie (SAM) | |||
| 5 | O (A) | P1-7-METHYLGUANOSINE-P3-ADENOSINE-5',5'-TRIPHOSPHATE | non-polymer | 787.4 | 1 | Chemie (GTA) | |||
| 6 | P (A) | 7-METHYL-GUANOSINE-5'-TRIPHOSPHATE | non-polymer | 538.2 | 1 | Chemie (MGP) | |||
| 7 | Q, R (A) | ADENINE | non-polymer | 135.1 | 2 | Chemie (ADE) | |||
| 8 | FA, GA, S, T, U... (B, A) | SULFATE ION | non-polymer | 96.1 | 10 | Chemie (SO4) | |||
| 9 | AA, BA (B) | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 10 | HA, IA (A, B) | water | water | 18.0 | 324 | Chemie (HOH) |
Sequence modifications
A: 6799 - 7096 (UniProt: P0DTD1)
B: 4254 - 4392 (UniProt: P0DTD1)
| PDB | External Database | Details |
|---|---|---|
| Ser 6796 | - | expression tag |
| Asn 6797 | - | expression tag |
| Ala 6798 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Ser 4251 | - | expression tag |
| Asn 4252 | - | expression tag |
| Ala 4253 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 48702.7 | |
| Non-Polymers* | Number of molecules | 31 |
| Total formula weight | 3582.1 | |
| All* | Total formula weight | 52284.8 |
