6WJT

2.0 Angstrom Resolution Crystal Structure of Nsp16-Nsp10 Heterodimer from SARS-CoV-2 in Complex with S-Adenosyl-L-Homocysteine

Summary for 6WJT

• Entry DOI: 10.2210/pdb6wjt/pdb
• Related: 6w75
• Descriptor: 2'-O-methyltransferase, Non-structural protein 10, SODIUM ION, ... (7 entities in total)
• Functional Keywords: structural genomics, center for structural genomics of infectious diseases, csgid, nsp16, nsp10, complex, viral protein, s-adenosyl-l-homocysteine
• Biological source: Severe acute respiratory syndrome coronavirus 2 (2019-nCoV); More
• Total number of polymer chains: 4
• Total formula weight: 99080.15

Authors

Minasov, G.,Shuvalova, L.,Rosas-Lemus, M.,Kiryukhina, O.,Satchell, K.J.F.,Center for Structural Genomics of Infectious Diseases (CSGID) (deposition date: 2020-04-14, release date: 2020-04-22, Last modification date: 2023-10-18)

• Primary citation: Rosas-Lemus, M.,Minasov, G.,Shuvalova, L.,Inniss, N.L.,Kiryukhina, O.,Brunzelle, J.,Satchell, K.J.F.; High-resolution structures of the SARS-CoV-2 2'- O -methyltransferase reveal strategies for structure-based inhibitor design.; Sci.Signal., 13:-, 2020; PubMed: 32994211; DOI: 10.1126/scisignal.abe1202

Experimental method

X-RAY DIFFRACTION (2 Å)