6WJT

2.0 Angstrom Resolution Crystal Structure of Nsp16-Nsp10 Heterodimer from SARS-CoV-2 in Complex with S-Adenosyl-L-Homocysteine

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C	2'-O-methyltransferase	polymer	301	33627.5	2	UniProt (P0DTD1) Pfam (PF06460) In PDB	Severe acute respiratory syndrome coronavirus 2 (2019-nCoV)	Non-structural protein 16
2	B, D	Non-structural protein 10	polymer	142	15075.2	2	UniProt (P0DTD1) Pfam (PF09401) In PDB	Severe acute respiratory syndrome coronavirus 2 (2019-nCoV)
3	A, C	SODIUM ION	non-polymer		23.0	2	Chemie (NA)
4	A, C	S-ADENOSYL-L-HOMOCYSTEINE	non-polymer		384.4	2	Chemie (SAH)
5	A, B, C	FORMIC ACID	non-polymer		46.0	13	Chemie (FMT)
6	B, D	ZINC ION	non-polymer		65.4	4	Chemie (ZN)
7		water	water		18.0	573	Chemie (HOH)

Sequence modifications

A, C: 6799 - 7096 (UniProt: P0DTD1)

PDB	External Database	Details
Ser 6796	-	expression tag
Asn 6797	-	expression tag
Ala 6798	-	expression tag

B, D: 4254 - 4392 (UniProt: P0DTD1)

PDB	External Database	Details
Ser 4251	-	expression tag
Asn 4252	-	expression tag
Ala 4253	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	97405.4
Non-Polymers*	Number of molecules	21
	Total formula weight	1674.8
All*	Total formula weight	99080.2

*Water molecules are not included.