6VK2

NMR solution structure of Grb2-SH2 domain at pH 7

Summary for 6VK2

• Entry DOI: 10.2210/pdb6vk2/pdb
• Related: 1BM2 1BMB 1FHS 1JYQ 1JYR 1JYU 1QG1 1TZE 1ZFP 2AOA 2H46 2H5K 2HOW 3C7I 3IMD 3IMJ 3IN7 3KFJ 3MXC 3N7Y 3N84 3N8M 3OV1 3S8L 3WA4
• NMR Information: BMRB: 27781
• Descriptor: Growth factor receptor-bound protein 2 (1 entity in total)
• Functional Keywords: grb2, sh2 domain, dynamics, cell cycle
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 1
• Total formula weight: 11204.76

Authors

Sanches, K.,Caruso, I.P.,Melo, F.A.,Almeida, F.C.L. (deposition date: 2020-01-18, release date: 2020-07-29, Last modification date: 2024-05-15)

• Primary citation: Sanches, K.,Caruso, I.P.,Almeida, F.C.L.,Melo, F.A.; The dynamics of free and phosphopeptide-bound Grb2-SH2 reveals two dynamically independent subdomains and an encounter complex with fuzzy interactions.; Sci Rep, 10:13040-13040, 2020; PubMed: 32747626; DOI: 10.1038/s41598-020-70034-w

Experimental method

SOLUTION NMR