2H46

Native domain-swapped dimer crystal structure of the Grb2 SH2 domain

Summary for 2H46

Entry DOI	10.2210/pdb2h46/pdb
Descriptor	Growth Receptor Binding Protein 2, GLYCEROL (3 entities in total)
Functional Keywords	helix-sheet-helix, hormone-growth factor complex, hormone/growth factor
Biological source	Homo sapiens (human)
Total number of polymer chains	1
Total formula weight	13779.56
Authors	Benfield, A.P.,Martin, S.F.,Whiddon, B.B. (deposition date: 2006-05-23, release date: 2006-06-06, Last modification date: 2024-02-14)
Primary citation	Benfield, A.P.,Whiddon, B.B.,Clements, J.H.,Martin, S.F. Structural and energetic aspects of Grb2-SH2 domain-swapping. Arch.Biochem.Biophys., 462:47-53, 2007 Cited by PubMed: 17466257 DOI: 10.1016/j.abb.2007.03.010 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.9 Å)

Structure validation