2H46
Native domain-swapped dimer crystal structure of the Grb2 SH2 domain
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (E) | Growth Receptor Binding Protein 2 | polymer | 116 | 13687.5 | 1 | UniProt (Q6ICN0) Pfam (PF00017) UniProt (by SIFTS) (P62993) | Homo sapiens (human) | Grb2 |
| 2 | B (E) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 3 | C (E) | water | water | 18.0 | 72 | Chemie (HOH) |
Sequence modifications
E: 53 - 162 (UniProt: Q6ICN0)
| PDB | External Database | Details |
|---|---|---|
| His 163 | - | expression tag |
| His 164 | - | expression tag |
| His 165 | - | expression tag |
| His 166 | - | expression tag |
| His 167 | - | expression tag |
| His 168 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 13687.5 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 92.1 | |
| All* | Total formula weight | 13779.6 |
