3S8L

Protein-Ligand Interactions: Thermodynamic Effects Associated with Increasing Hydrophobic Surface Area

Summary for 3S8L

Entry DOI	10.2210/pdb3s8l/pdb
Related	3OV1 3OVE 3S8N 3S8O
Descriptor	Growth factor receptor-bound protein 2, pYAc4cN, CHLORIDE ION, ... (5 entities in total)
Functional Keywords	grb2 sh2 domain, phosphotyrosine-containing tripeptide, signaling protein-antagonist complex, signaling protein/antagonist
Biological source	Homo sapiens (human)
Cellular location	Nucleus: P62993
Total number of polymer chains	2
Total formula weight	14382.52
Authors	Clements, J.H.,Stephen, F.M. (deposition date: 2011-05-29, release date: 2011-11-02, Last modification date: 2023-12-06)
Primary citation	Myslinski, J.M.,Delorbe, J.E.,Clements, J.H.,Martin, S.F. Protein-ligand interactions: thermodynamic effects associated with increasing nonpolar surface area. J.Am.Chem.Soc., 133:18518-18521, 2011 Cited by PubMed: 22007755 DOI: 10.1021/ja2068752 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.71 Å)

Structure validation