3S8L
Protein-Ligand Interactions: Thermodynamic Effects Associated with Increasing Hydrophobic Surface Area
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Growth factor receptor-bound protein 2 | polymer | 117 | 13758.5 | 1 | UniProt (P62993) Pfam (PF00017) | Homo sapiens (human) | Adapter protein GRB2, Protein Ash, SH2/SH3 adapter GRB2 |
| 2 | B (B) | pYAc4cN | polymer | 5 | 496.4 | 1 | |||
| 3 | C (A) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
| 4 | D (A) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 5 | E, F (A, B) | water | water | 18.0 | 58 | Chemie (HOH) |
Sequence modifications
A: 53 - 163 (UniProt: P62993)
| PDB | External Database | Details |
|---|---|---|
| His 164 | - | expression tag |
| His 165 | - | expression tag |
| His 166 | - | expression tag |
| His 167 | - | expression tag |
| His 168 | - | expression tag |
| His 169 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 14255.0 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 127.5 | |
| All* | Total formula weight | 14382.5 |
