3S8L
Protein-Ligand Interactions: Thermodynamic Effects Associated with Increasing Hydrophobic Surface Area
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE CL A 1 |
| Chain | Residue |
| A | SER139 |
| A | GLN145 |
| site_id | AC2 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE GOL A 2 |
| Chain | Residue |
| A | SER75 |
| A | GLN77 |
| A | ARG78 |
| A | ASP94 |
| A | LYS100 |
| A | ARG112 |
| A | HOH174 |
| site_id | AC3 |
| Number of Residues | 17 |
| Details | BINDING SITE FOR CHAIN B OF PYAC4CN |
| Chain | Residue |
| A | HOH7 |
| A | ARG67 |
| A | ARG78 |
| A | ARG86 |
| A | SER88 |
| A | SER90 |
| A | SER96 |
| A | HIS107 |
| A | PHE108 |
| A | LYS109 |
| A | LEU120 |
| A | TRP121 |
| A | VAL154 |
| B | HOH6 |
| B | HOH46 |
| B | HOH47 |
| B | HOH48 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 92 |
| Details | Domain: {"description":"SH2","evidences":[{"source":"PROSITE-ProRule","id":"PRU00191","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"PubMed","id":"19608861","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin)","evidences":[{"source":"PubMed","id":"34348893","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
