3S8O
Crystal Structure of the Grb2 SH2 Domain in Complex with a pYXN-Derived Tripeptide
Summary for 3S8O
Entry DOI | 10.2210/pdb3s8o/pdb |
Related | 3OV1 3OVE 3S8L 3S8N |
Descriptor | Growth factor receptor-bound protein 2, pYAc6cN, SODIUM ION, ... (5 entities in total) |
Functional Keywords | grb2 sh2 domain, phosphotyrosine-containing tripeptide, signaling protein-antagonist complex, signaling protein/antagonist |
Biological source | Homo sapiens (human) |
Cellular location | Nucleus: P62993 |
Total number of polymer chains | 2 |
Total formula weight | 14341.47 |
Authors | Clements, J.H.,Stephen, F.M. (deposition date: 2011-05-29, release date: 2011-11-02, Last modification date: 2023-12-06) |
Primary citation | Myslinski, J.M.,Delorbe, J.E.,Clements, J.H.,Martin, S.F. Protein-ligand interactions: thermodynamic effects associated with increasing nonpolar surface area. J.Am.Chem.Soc., 133:18518-18521, 2011 Cited by PubMed: 22007755DOI: 10.1021/ja2068752 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.85 Å) |
Structure validation
Download full validation report