5UPV

Crystal Structure of the Catalytic Domain of the Inosine Monophosphate Dehydrogenase from Mycobacterium tuberculosis In the presence of G36

Summary for 5UPV

• Entry DOI: 10.2210/pdb5upv/pdb
• Related: 4ZQM 4ZQN 4ZQO 4ZQP 4ZQR 5UPU
• Descriptor: Inosine-5'-monophosphate dehydrogenase, INOSINIC ACID, N-{(1S)-1-[3-methoxy-4-(1,3-oxazol-5-yl)phenyl]ethyl}-N'-phenylurea, ... (6 entities in total)
• Functional Keywords: impdh, delta cbs, structural genomics, center for structural genomics of infectious diseases, csgid, oxidoreductase, oxidoreductase-oxidoreductase inhibitor complex, oxidoreductase/oxidoreductase inhibitor
• Biological source: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv); More
• Total number of polymer chains: 1
• Total formula weight: 42652.48

Authors

Kim, Y.,Maltseva, N.,Mulligan, R.,Makowska-Grzyska, M.,Gu, M.,Anderson, W.F.,Joachimiak, A.,Center for Structural Genomics of Infectious Diseases (CSGID) (deposition date: 2017-02-04, release date: 2017-02-22, Last modification date: 2023-10-04)

• Primary citation: Kim, Y.,Maltseva, N.,Mulligan, R.,Makowska-Grzyska, M.,Gu, M.,Anderson, W.F.,Joachimiak, A.,Center for Structural Genomics of Infectious Diseases (CSGID); Crystal Structure of the Catalytic Domain of the Inosine Monophosphate Dehydrogenase from Mycobacterium tuberculosis In the presence of G36; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.63 Å)