4ZQR

Crystal Structure of the Catalytic Domain of the Inosine Monophosphate Dehydrogenase from Mycobacterium tuberculosis

Summary for 4ZQR

Entry DOI	10.2210/pdb4zqr/pdb
Related	4ZQM 4ZQN 4ZQO 4ZQP
Descriptor	Inosine-5'-monophosphate dehydrogenase,Inosine-5'-monophosphate dehydrogenase, PHOSPHATE ION, S-1,2-PROPANEDIOL, ... (6 entities in total)
Functional Keywords	impdh, delta cbs, structural genomics, center for structural genomics of infectious diseases, csgid, oxidoreductase
Biological source	Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Total number of polymer chains	4
Total formula weight	169261.20
Authors	Kim, Y.,Makowska-Grzyska, M.,Gu, M.,Kavitha, M.,Hedstrom, L.,Anderson, W.F.,Joachimiak, A.,Center for Structural Genomics of Infectious Diseases (CSGID) (deposition date: 2015-05-11, release date: 2015-06-17, Last modification date: 2022-03-30)
Primary citation	Makowska-Grzyska, M.,Kim, Y.,Gorla, S.K.,Wei, Y.,Mandapati, K.,Zhang, M.,Maltseva, N.,Modi, G.,Boshoff, H.I.,Gu, M.,Aldrich, C.,Cuny, G.D.,Hedstrom, L.,Joachimiak, A. Mycobacterium tuberculosis IMPDH in Complexes with Substrates, Products and Antitubercular Compounds. Plos One, 10:e0138976-e0138976, 2015 Cited by PubMed: 26440283 DOI: 10.1371/journal.pone.0138976 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.692 Å)

Structure validation