4ZQR
Crystal Structure of the Catalytic Domain of the Inosine Monophosphate Dehydrogenase from Mycobacterium tuberculosis
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Inosine-5'-monophosphate dehydrogenase,Inosine-5'-monophosphate dehydrogenase | polymer | 407 | 41642.6 | 4 | UniProt (P9WKI7) Pfam (PF00478) | Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) | IMPDH |
| 2 | E, HA, P, Z (A, D, B, C) | PHOSPHATE ION | non-polymer | 95.0 | 4 | Chemie (PO4) | |||
| 3 | AA, EA, F, FA, G... (C, A, D, B) | S-1,2-PROPANEDIOL | non-polymer | 76.1 | 15 | Chemie (PGO) | |||
| 4 | BA, CA, DA, GA, J... (C, D, A, B) | GLYCEROL | non-polymer | 92.1 | 11 | Chemie (GOL) | |||
| 5 | M, O, T, X (A, B) | POTASSIUM ION | non-polymer | 39.1 | 4 | Chemie (K) | |||
| 6 | MA, NA, OA, PA (A, B, C, D) | water | water | 18.0 | 793 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 1 - 125 (UniProt: P9WKI7)
A, B, C, D: 253 - 529 (UniProt: P9WKI7)
| PDB | External Database | Details |
|---|---|---|
| Ser -2 | - | expression tag |
| Asn -1 | - | expression tag |
| Ala 0 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Gly 126 | - | linker |
| Gly 127 | - | linker |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 166570.5 | |
| Non-Polymers* | Number of molecules | 34 |
| Total formula weight | 2690.7 | |
| All* | Total formula weight | 169261.2 |
