4ZQM

Crystal Structure of the Catalytic Domain of the Inosine Monophosphate Dehydrogenase from Mycobacterium tuberculosis in the complex with XMP and NAD

Summary for 4ZQM

Entry DOI	10.2210/pdb4zqm/pdb
Related	4ZQN 4ZQO 4ZQP 4ZQR
Descriptor	Inosine-5'-monophosphate dehydrogenase,Inosine-5'-monophosphate dehydrogenase, XANTHOSINE-5'-MONOPHOSPHATE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ... (4 entities in total)
Functional Keywords	impdh, delta-cbs, mycobacterium tuberculosis, structural genomics, center for structural genomics of infectious diseases, csgid, oxidoreductase
Biological source	Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Total number of polymer chains	1
Total formula weight	42671.26
Authors	Kim, Y.,Maltseva, N.,Makowska-Grzyska, M.,Gu, M.,Kavitha, M.,Hedstrom, L.,Anderson, W.F.,Joachimiak, A.,Center for Structural Genomics of Infectious Diseases (CSGID) (deposition date: 2015-05-10, release date: 2015-06-17, Last modification date: 2022-03-30)
Primary citation	Makowska-Grzyska, M.,Kim, Y.,Gorla, S.K.,Wei, Y.,Mandapati, K.,Zhang, M.,Maltseva, N.,Modi, G.,Boshoff, H.I.,Gu, M.,Aldrich, C.,Cuny, G.D.,Hedstrom, L.,Joachimiak, A. Mycobacterium tuberculosis IMPDH in Complexes with Substrates, Products and Antitubercular Compounds. Plos One, 10:e0138976-e0138976, 2015 Cited by PubMed: 26440283 DOI: 10.1371/journal.pone.0138976 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.602 Å)

Structure validation