Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003824 | molecular_function | catalytic activity |
| A | 0003938 | molecular_function | IMP dehydrogenase activity |
| A | 0006164 | biological_process | purine nucleotide biosynthetic process |
| A | 0016491 | molecular_function | oxidoreductase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 26 |
| Details | binding site for residue XMP A 601 |
| Chain | Residue |
| A | SER83 |
| A | GLY375 |
| A | GLY376 |
| A | MET395 |
| A | GLY397 |
| A | SER398 |
| A | TYR421 |
| A | GLY423 |
| A | MET424 |
| A | GLY425 |
| A | GLU458 |
| A | MET85 |
| A | GLY459 |
| A | NAD602 |
| A | HOH725 |
| A | HOH762 |
| A | HOH765 |
| A | HOH780 |
| A | HOH820 |
| A | ASN313 |
| A | GLY338 |
| A | SER339 |
| A | ILE340 |
| A | CYS341 |
| A | THR343 |
| A | ASP374 |
| site_id | AC2 |
| Number of Residues | 19 |
| Details | binding site for residue NAD A 602 |
| Chain | Residue |
| A | VAL59 |
| A | ARG108 |
| A | ASP283 |
| A | THR284 |
| A | ALA285 |
| A | HIS286 |
| A | ASN289 |
| A | THR343 |
| A | MET424 |
| A | GLU458 |
| A | ALA483 |
| A | GLY486 |
| A | TYR487 |
| A | XMP601 |
| A | HOH707 |
| A | HOH708 |
| A | HOH724 |
| A | HOH727 |
| A | HOH741 |
Functional Information from PROSITE/UniProt
| site_id | PS00487 |
| Number of Residues | 13 |
| Details | IMP_DH_GMP_RED IMP dehydrogenase / GMP reductase signature. VKVGVGpGSICtT |
| Chain | Residue | Details |
| A | VAL331-THR343 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | Active site: {"description":"Thioimidate intermediate","evidences":[{"source":"HAMAP-Rule","id":"MF_01964","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"26440283","evidenceCode":"ECO:0000305"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 9 |
| Details | Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_01964","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"26440283","evidenceCode":"ECO:0000269"}]} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 3 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"26440283","evidenceCode":"ECO:0000269"}]} |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_01964","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI5 |
| Number of Residues | 3 |
| Details | Binding site: {"description":"in other chain","evidences":[{"source":"HAMAP-Rule","id":"MF_01964","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"26440283","evidenceCode":"ECO:0000269"}]} |
