5UPV
Crystal Structure of the Catalytic Domain of the Inosine Monophosphate Dehydrogenase from Mycobacterium tuberculosis In the presence of G36
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Inosine-5'-monophosphate dehydrogenase | polymer | 407 | 41642.6 | 1 | UniProt (P9WKI7) Pfam (PF00478) | Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) | IMPDH,IMPDH2 |
| 2 | B (A) | INOSINIC ACID | non-polymer | 348.2 | 1 | Chemie (IMP) | |||
| 3 | C (A) | N-{(1S)-1-[3-methoxy-4-(1,3-oxazol-5-yl)phenyl]ethyl}-N'-phenylurea | non-polymer | 337.4 | 1 | Chemie (8KV) | |||
| 4 | D, F, I (A) | FORMIC ACID | non-polymer | 46.0 | 3 | Chemie (FMT) | |||
| 5 | E, G, H (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 3 | Chemie (EDO) | |||
| 6 | J (A) | water | water | 18.0 | 159 | Chemie (HOH) |
Sequence modifications
A: 1 - 125 (UniProt: P9WKI7)
A: 256 - 529 (UniProt: P9WKI7)
| PDB | External Database | Details |
|---|---|---|
| Ser -2 | - | expression tag |
| Asn -1 | - | expression tag |
| Ala 0 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Gly 126 | - | linker |
| Gly 127 | - | linker |
| Leu 253 | - | linker |
| Leu 254 | - | linker |
| Val 255 | - | linker |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 41642.6 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 1009.9 | |
| All* | Total formula weight | 42652.5 |
