5NI6

Crystal structure of human LTA4H mutant D375N in complex with LTA4

Summary for 5NI6

Entry DOI	10.2210/pdb5ni6/pdb
Related	4DPR 4MS6 5NI2 5NI4
Descriptor	Leukotriene A-4 hydrolase, ZINC ION, YTTERBIUM (III) ION, ... (6 entities in total)
Functional Keywords	metallopeptidase, epoxide hydrolase, leukotriene a4, hydrolase
Biological source	Homo sapiens (Human)
Cellular location	Cytoplasm: P09960
Total number of polymer chains	1
Total formula weight	71041.91
Authors	Stsiapanava, A. (deposition date: 2017-03-23, release date: 2017-08-23, Last modification date: 2024-01-17)
Primary citation	Stsiapanava, A.,Samuelsson, B.,Haeggstrom, J.Z. Capturing LTA4 hydrolase in action: Insights to the chemistry and dynamics of chemotactic LTB4 synthesis. Proc. Natl. Acad. Sci. U.S.A., 114:9689-9694, 2017 Cited by PubMed: 28827365 DOI: 10.1073/pnas.1710850114 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.54 Å)

Structure validation