5NI2

Crystal structure of human LTA4H mutant E271A in complex with LTA4 (crystal form I)

Summary for 5NI2

Entry DOI	10.2210/pdb5ni2/pdb
Related	4DPR 4MS6
Descriptor	Leukotriene A-4 hydrolase, ZINC ION, YTTERBIUM (III) ION, ... (5 entities in total)
Functional Keywords	metallopeptidase, epoxide hydrolase, leukotriene a4, hydrolase
Biological source	Homo sapiens (Human)
Cellular location	Cytoplasm: P09960
Total number of polymer chains	1
Total formula weight	70864.76
Authors	Stsiapanava, A. (deposition date: 2017-03-23, release date: 2017-08-23, Last modification date: 2017-09-13)
Primary citation	Stsiapanava, A.,Samuelsson, B.,Haeggstrom, J.Z. Capturing LTA4 hydrolase in action: Insights to the chemistry and dynamics of chemotactic LTB4 synthesis. Proc. Natl. Acad. Sci. U.S.A., 114:9689-9694, 2017 Cited by PubMed: 28827365 DOI: 10.1073/pnas.1710850114 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.501 Å)

Structure validation