5NI4
Crystal structure of human LTA4H mutant E271A in complex with LTA4 (crystal form II)
Summary for 5NI4
| Entry DOI | 10.2210/pdb5ni4/pdb |
| Related | 4DPR 4MS6 5NI2 |
| Descriptor | Leukotriene A-4 hydrolase, ZINC ION, IMIDAZOLE, ... (5 entities in total) |
| Functional Keywords | metallopeptidase, epoxide hydrolase, leukotriene a4, hydrolase |
| Biological source | Homo sapiens (Human) |
| Cellular location | Cytoplasm: P09960 |
| Total number of polymer chains | 3 |
| Total formula weight | 212039.63 |
| Authors | Stsiapanava, A. (deposition date: 2017-03-23, release date: 2017-08-23, Last modification date: 2024-01-17) |
| Primary citation | Stsiapanava, A.,Samuelsson, B.,Haeggstrom, J.Z. Capturing LTA4 hydrolase in action: Insights to the chemistry and dynamics of chemotactic LTB4 synthesis. Proc. Natl. Acad. Sci. U.S.A., 114:9689-9694, 2017 Cited by PubMed: 28827365DOI: 10.1073/pnas.1710850114 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.895 Å) |
Structure validation
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