5EU9
Structure of Human Enolase 2 in complex with ((3S,5S)-1,5-dihydroxy-3-methyl-2-oxopyrrolidin-3-yl)phosphonic acid
Summary for 5EU9
Entry DOI | 10.2210/pdb5eu9/pdb |
Related | 1TE6 2AKM 2AKZ 3UCC 3UCD 3UJE 3UJF 3UJR 3UJS 4ZA0 4ZCW |
Descriptor | Gamma-enolase, MAGNESIUM ION, ((3S,5S)-1,5-dihydroxy-3-methyl-2-oxopyrrolidin-3-yl)phosphonic acid, ... (5 entities in total) |
Functional Keywords | enolase gamma, glycolysis, neuron specific enolase, carbohydrate metabolism, lyase-lyase inhibitor complex, lyase/lyase inhibitor |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 8 |
Total formula weight | 388172.96 |
Authors | Leonard, P.G.,Muller, F.L. (deposition date: 2015-11-18, release date: 2016-11-23, Last modification date: 2023-09-27) |
Primary citation | Leonard, P.G.,Maxwell, D.,Satani, N.,Peng, Z.,Link, T.,Lee, G.,Bosajou, A.,Sun, D.,Lin, Y.E.,DiFrancesco, M.E.,Czako, B.,Wang, Y.A.,Bornmann, W.,DePhinho, R.A.,Muller, F.L. SF2312, a natural phosphonate inhibitor of Enolase To be Published, |
Experimental method | X-RAY DIFFRACTION (2.047 Å) |
Structure validation
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