5EU9

Structure of Human Enolase 2 in complex with ((3S,5S)-1,5-dihydroxy-3-methyl-2-oxopyrrolidin-3-yl)phosphonic acid

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, E...	Gamma-enolase	polymer	440	48149.3	8	UniProt (P09104) Pfam (PF03952) Pfam (PF00113) In PDB	Homo sapiens (Human)	2-phospho-D-glycerate hydro-lyase, Enolase 2, Neural enolase, Neuron-specific enolase, NSE
2	F, G, A, H, B...	MAGNESIUM ION	non-polymer		24.3	16	Chemie (MG)
3	F, G, A, H, B...	((3S,5S)-1,5-dihydroxy-3-methyl-2-oxopyrrolidin-3-yl)phosphonic acid	non-polymer		211.1	8	Chemie (5TX)
4	F, G, H, C, D...	TRIETHYLENE GLYCOL	non-polymer		150.2	6	Chemie (PGE)
5		water	water		18.0	2238	Chemie (HOH)

Sequence modifications

A, B, C, D, E, F, G, H: 1 - 434 (UniProt: P09104)

PDB	External Database	Details
His 435	-	expression tag
His 436	-	expression tag
His 437	-	expression tag
His 438	-	expression tag
His 439	-	expression tag
His 440	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	8
	Total formula weight	385194.2
Non-Polymers*	Number of molecules	30
	Total formula weight	2978.8
All*	Total formula weight	388173.0

*Water molecules are not included.