4PNK
G protein-coupled receptor kinase 2 in complex with GSK180736A
Summary for 4PNK
Entry DOI | 10.2210/pdb4pnk/pdb |
Related | 3V5W 4MK0 4PNI |
Descriptor | Beta-adrenergic receptor kinase 1, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... (5 entities in total) |
Functional Keywords | protein kinase, hydrolase, atp binding, phosphorylation, peripheral membrane protein, transferase-transferase inhibitor complex, transferase/transferase inhibitor |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 3 |
Total formula weight | 125320.01 |
Authors | Homan, K.T.,Larimore, K.M.,Elkins, J.,Knapp, S.,Tesmer, J.J.G. (deposition date: 2014-05-23, release date: 2014-10-08, Last modification date: 2023-12-27) |
Primary citation | Homan, K.T.,Larimore, K.M.,Elkins, J.M.,Szklarz, M.,Knapp, S.,Tesmer, J.J. Identification and structure-function analysis of subfamily selective g protein-coupled receptor kinase inhibitors. Acs Chem.Biol., 10:310-319, 2015 Cited by PubMed: 25238254DOI: 10.1021/cb5006323 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.56 Å) |
Structure validation
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