4I3H
A three-gate structure of topoisomerase IV from Streptococcus pneumoniae
Summary for 4I3H
Entry DOI | 10.2210/pdb4i3h/pdb |
Related | 1EI1 2NOV 3FOE 3FOF 3K9F 3KSA 3KSB 3LTN 3RAD 3RAE 3RAF 4GFH |
Descriptor | DNA (5'-D(*CP*AP*AP*AP*GP*GP*CP*GP*GP*TP*AP*AP*TP*AP*CP*GP*GP*TP*TP*AP*TP*CP*CP*AP*CP*AP*GP*AP*AP*TP*CP*AP*GP*G)-3'), DNA (5'-D(*CP*CP*TP*GP*AP*TP*TP*CP*TP*GP*TP*GP*GP*AP*TP*AP*AP*CP*CP*GP*TP*AP*TP*TP*AP*CP*CP*GP*CP*CP*TP*TP*TP*G)-3'), Topoisomerase IV subunit B, DNA topoisomerase 4 subunit A chimera, ... (5 entities in total) |
Functional Keywords | dna unwinding, supercoiling, isomerase-dna complex, isomerase/dna |
Biological source | Streptococcus pneumoniae More |
Cellular location | Cell membrane ; Peripheral membrane protein : D6ZLV0 |
Total number of polymer chains | 6 |
Total formula weight | 298555.59 |
Authors | Laponogov, I.,Veselkov, D.A.,Pan, X.-S.,Crevel, I.,Fisher, L.M.,Sanderson, M.R. (deposition date: 2012-11-26, release date: 2013-08-28, Last modification date: 2023-09-20) |
Primary citation | Laponogov, I.,Veselkov, D.A.,Crevel, I.M.,Pan, X.S.,Fisher, L.M.,Sanderson, M.R. Structure of an 'open' clamp type II topoisomerase-DNA complex provides a mechanism for DNA capture and transport. Nucleic Acids Res., 41:9911-9923, 2013 Cited by PubMed: 23965305DOI: 10.1093/nar/gkt749 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.7 Å) |
Structure validation
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