4I3H

A three-gate structure of topoisomerase IV from Streptococcus pneumoniae

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	E, G	DNA (5'-D(*CP*AP*AP*AP*GP*GP*CP*GP*GP*TP*AP*AP*TP*AP*CP*GP*GP*TP*TP*AP*TP*CP*CP*AP*CP*AP*GP*AP*AP*TP*CP*AP*GP*G)-3')	polymer	34	10525.8	2
2	F, H	DNA (5'-D(*CP*CP*TP*GP*AP*TP*TP*CP*TP*GP*TP*GP*GP*AP*TP*AP*AP*CP*CP*GP*TP*AP*TP*TP*AP*CP*CP*GP*CP*CP*TP*TP*TP*G)-3')	polymer	34	10391.7	2
3	A, B	Topoisomerase IV subunit B, DNA topoisomerase 4 subunit A chimera	polymer	1144	128323.9	2	UniProt (Q3HZ71) UniProt (D6ZLV0) Pfam (PF02518) Pfam (PF00204) Pfam (PF01751) Pfam (PF00986) Pfam (PF00521) UniProt (by SIFTS) (Q59961) UniProt (by SIFTS) (P72525) In PDB	Streptococcus pneumoniae
4	A, B, H	MAGNESIUM ION	non-polymer		24.3	3	Chemie (MG)
5		water	water		18.0	2	Chemie (HOH)

Sequence modifications

A, B: 1 - 999 (UniProt: Q3HZ71)

PDB	External Database	Details
His 1000	-	linker

A, B: 1001 - 1488 (UniProt: D6ZLV0)

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	298482.7
Non-Polymers*	Number of molecules	3
	Total formula weight	72.9
All*	Total formula weight	298555.6

*Water molecules are not included.