3RAE
Quinolone(Levofloxacin)-DNA cleavage complex of type IV topoisomerase from S. pneumoniae
Summary for 3RAE
Entry DOI | 10.2210/pdb3rae/pdb |
Related | 2NOV 3FOE 3FOF 3K9F 3KSA 3KSB 3LTN 3RAD 3RAF |
Descriptor | DNA topoisomerase 4 subunit A, DNA topoisomerase 4 subunit B, 5'-D(*CP*AP*TP*GP*AP*AP*T)-3', ... (9 entities in total) |
Functional Keywords | protein-dna cleavage complex, topoisomerase iia, levofloxacin, isomerase-dna-antibiotic complex, isomerase/dna/antibiotic |
Biological source | Streptococcus pneumoniae More |
Cellular location | Cell membrane ; Peripheral membrane protein : P72525 |
Total number of polymer chains | 8 |
Total formula weight | 185552.11 |
Authors | Laponogov, I.,Pan, X.-S.,Veselkov, D.A.,McAuley, K.E.,Fisher, L.M.,Sanderson, M.R. (deposition date: 2011-03-28, release date: 2012-04-25, Last modification date: 2023-11-01) |
Primary citation | Veselkov, D.A.,Laponogov, I.,Pan, X.S.,Selvarajah, J.,Skamrova, G.B.,Branstrom, A.,Narasimhan, J.,Prasad, J.V.,Fisher, L.M.,Sanderson, M.R. Structure of a quinolone-stabilized cleavage complex of topoisomerase IV from Klebsiella pneumoniae and comparison with a related Streptococcus pneumoniae complex. Acta Crystallogr.,Sect.D, 72:488-496, 2016 Cited by PubMed: 27050128DOI: 10.1107/S2059798316001212 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.9 Å) |
Structure validation
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