4AJS
3D structure of E. coli Isocitrate Dehydrogenase K100M mutant in complex with isocitrate, magnesium(II), Adenosine 2',5'-biphosphate and ribosylnicotinamide-5'-phosphate
Summary for 4AJS
Entry DOI | 10.2210/pdb4ajs/pdb |
Related | 1AI2 1AI3 1BL5 1CW1 1CW4 1CW7 1GRO 1GRP 1HJ6 1IDC 1IDD 1IDE 1IDF 1IKA 1ISO 1P8F 1PB1 1PB3 1SJS 3ICD 4AJR 4ICD 5ICD 6ICD 7ICD 8ICD 9ICD |
Descriptor | ISOCITRATE DEHYDROGENASE [NADP], ADENOSINE-2'-5'-DIPHOSPHATE, ISOCITRIC ACID, ... (7 entities in total) |
Functional Keywords | oxidoreductase, oxidative beta-decarboxylation |
Biological source | ESCHERICHIA COLI |
Total number of polymer chains | 1 |
Total formula weight | 46886.50 |
Authors | Goncalves, S.,Miller, S.P.,Carrondo, M.A.,Dean, A.M.,Matias, P.M. (deposition date: 2012-02-17, release date: 2012-10-31, Last modification date: 2023-12-20) |
Primary citation | Goncalves, S.,Miller, S.P.,Carrondo, M.A.,Dean, A.M.,Matias, P.M. Induced Fit and the Catalytic Mechanism of Isocitrate Dehydrogenase. Biochemistry, 51:7098-, 2012 Cited by PubMed: 22891681DOI: 10.1021/BI300483W PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.802 Å) |
Structure validation
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