4AFT
Aplysia californica AChBP in complex with Varenicline
Summary for 4AFT
Entry DOI | 10.2210/pdb4aft/pdb |
Related | 2BR7 2BR8 2BYN 2BYP 2BYQ 2BYR 2BYS 2C9T 2UZ6 2W8F 2W8G 2WN9 2WNC 2WNJ 2WNL 2WZY 2X00 2XNT 2XNU 2XNV 2XYS 2XYT 2XZ5 2XZ6 2Y54 2Y56 2Y57 2Y58 2Y7Y 4AFO 4AFW |
Descriptor | SOLUBLE ACETYLCHOLINE RECEPTOR, VARENICLINE (2 entities in total) |
Functional Keywords | receptor protein, nicotinic |
Biological source | APLYSIA CALIFORNICA (CALIFORNIA SEA HARE) |
Total number of polymer chains | 5 |
Total formula weight | 124499.20 |
Authors | Rucktooa, P.,Haseler, C.A.,vanElke, R.,Smit, A.B.,Gallagher, T.,Sixma, T.K. (deposition date: 2012-01-23, release date: 2012-05-02, Last modification date: 2023-12-20) |
Primary citation | Rucktooa, P.,Haseler, C.A.,Van Elk, R.,Smit, A.B.,Gallagher, T.,Sixma, T.K. Structural Characterization of Binding Mode of Smoking Cessation Drugs to Nicotinic Acetylcholine Receptors Through Study of Ligand Complexes with Acetylcholine-Binding Protein. J.Biol.Chem., 287:23283-, 2012 Cited by PubMed: 22553201DOI: 10.1074/JBC.M112.360347 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.2 Å) |
Structure validation
Download full validation report