4AFT

Aplysia californica AChBP in complex with Varenicline

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004888	molecular_function	transmembrane signaling receptor activity
A	0005216	molecular_function	monoatomic ion channel activity
A	0005230	molecular_function	extracellular ligand-gated monoatomic ion channel activity
A	0005515	molecular_function	protein binding
A	0006811	biological_process	monoatomic ion transport
A	0016020	cellular_component	membrane
A	0034220	biological_process	monoatomic ion transmembrane transport
A	0042802	molecular_function	identical protein binding
A	0046872	molecular_function	metal ion binding
B	0004888	molecular_function	transmembrane signaling receptor activity
B	0005216	molecular_function	monoatomic ion channel activity
B	0005230	molecular_function	extracellular ligand-gated monoatomic ion channel activity
B	0005515	molecular_function	protein binding
B	0006811	biological_process	monoatomic ion transport
B	0016020	cellular_component	membrane
B	0034220	biological_process	monoatomic ion transmembrane transport
B	0042802	molecular_function	identical protein binding
B	0046872	molecular_function	metal ion binding
C	0004888	molecular_function	transmembrane signaling receptor activity
C	0005216	molecular_function	monoatomic ion channel activity
C	0005230	molecular_function	extracellular ligand-gated monoatomic ion channel activity
C	0005515	molecular_function	protein binding
C	0006811	biological_process	monoatomic ion transport
C	0016020	cellular_component	membrane
C	0034220	biological_process	monoatomic ion transmembrane transport
C	0042802	molecular_function	identical protein binding
C	0046872	molecular_function	metal ion binding
D	0004888	molecular_function	transmembrane signaling receptor activity
D	0005216	molecular_function	monoatomic ion channel activity
D	0005230	molecular_function	extracellular ligand-gated monoatomic ion channel activity
D	0005515	molecular_function	protein binding
D	0006811	biological_process	monoatomic ion transport
D	0016020	cellular_component	membrane
D	0034220	biological_process	monoatomic ion transmembrane transport
D	0042802	molecular_function	identical protein binding
D	0046872	molecular_function	metal ion binding
E	0004888	molecular_function	transmembrane signaling receptor activity
E	0005216	molecular_function	monoatomic ion channel activity
E	0005230	molecular_function	extracellular ligand-gated monoatomic ion channel activity
E	0005515	molecular_function	protein binding
E	0006811	biological_process	monoatomic ion transport
E	0016020	cellular_component	membrane
E	0034220	biological_process	monoatomic ion transmembrane transport
E	0042802	molecular_function	identical protein binding
E	0046872	molecular_function	metal ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	7
Details	BINDING SITE FOR RESIDUE QMR A 301

Chain	Residue
A	TYR91
A	TRP145
A	TYR186
A	CYS188
A	TYR193
B	MET114
B	ILE116

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site_id	AC2
Number of Residues	7
Details	BINDING SITE FOR RESIDUE QMR B 301

Chain	Residue
B	TYR186
B	TYR193
C	VAL106
C	MET114
C	ILE116
B	TYR91
B	TRP145

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site_id	AC3
Number of Residues	7
Details	BINDING SITE FOR RESIDUE QMR C 301

Chain	Residue
C	TYR91
C	TRP145
C	TYR186
C	CYS188
C	TYR193
D	VAL106
D	ILE116

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site_id	AC4
Number of Residues	6
Details	BINDING SITE FOR RESIDUE QMR D 301

Chain	Residue
D	TYR91
D	TRP145
D	TYR186
D	TYR193
E	VAL106
E	ILE116

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site_id	AC5
Number of Residues	7
Details	BINDING SITE FOR RESIDUE QMR E 301

Chain	Residue
A	VAL106
A	ILE116
E	TYR91
E	TRP145
E	VAL146
E	TYR186
E	TYR193

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