2XYS

Crystal structure of Aplysia californica AChBP in complex with strychnine

Summary for 2XYS

Related2WN9 2W8F 2BYP 2C9T 2BYQ 2W8G 2X00 2UZ6 2WNL 2BR7 2BR8 2XNV 2BYR 2BYN 2BYS 2XNT 2WNJ 2Y7Y 2WZY 2WNC 2XNU 2XYT
DescriptorSOLUBLE ACETYLCHOLINE RECEPTOR, STRYCHNINE (3 entities in total)
Functional Keywordsreceptor, amidation, conformational flexibility, conotoxin, neurotoxin, nicotinic, postsynaptic neurotoxin, receptor-toxin complex
Biological sourceAPLYSIA CALIFORNICA (CALIFORNIA SEA HARE)
Total number of polymer chains5
Total molecular weight125449.36
Authors
Brams, M.,Pandya, A.,Kuzmin, D.,van Elk, R.,Krijnen, L.,Yakel, J.L.,Tsetlin, V.,Smit, A.B.,Ulens, C. (deposition date: 2010-11-19, release date: 2011-03-23, Last modification date: 2011-12-28)
Primary citation
Brams, M.,Pandya, A.,Kuzmin, D.,Van Elk, R.,Krijnen, L.,Yakel, J.L.,Tsetlin, V.,Smit, A.B.,Ulens, C.
A Structural and Mutagenic Blueprint for Molecular Recognition of Strychnine and D-Tubocurarine by Different Cys-Loop Receptors.
Plos Biol., 9:01034-, 2011
PubMed: 21468359 (PDB entries with the same primary citation)
DOI: 10.1371/JOURNAL.PBIO.1001034
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (1.909 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.20960 0.6% 2.5%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation reportDownload
169963
PDB entries from 2020-10-14