2XYS

Crystal structure of Aplysia californica AChBP in complex with strychnine

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004888	molecular_function	transmembrane signaling receptor activity
A	0005216	molecular_function	monoatomic ion channel activity
A	0005230	molecular_function	extracellular ligand-gated monoatomic ion channel activity
A	0005515	molecular_function	protein binding
A	0006811	biological_process	monoatomic ion transport
A	0016020	cellular_component	membrane
A	0034220	biological_process	monoatomic ion transmembrane transport
A	0042802	molecular_function	identical protein binding
A	0046872	molecular_function	metal ion binding
B	0004888	molecular_function	transmembrane signaling receptor activity
B	0005216	molecular_function	monoatomic ion channel activity
B	0005230	molecular_function	extracellular ligand-gated monoatomic ion channel activity
B	0005515	molecular_function	protein binding
B	0006811	biological_process	monoatomic ion transport
B	0016020	cellular_component	membrane
B	0034220	biological_process	monoatomic ion transmembrane transport
B	0042802	molecular_function	identical protein binding
B	0046872	molecular_function	metal ion binding
C	0004888	molecular_function	transmembrane signaling receptor activity
C	0005216	molecular_function	monoatomic ion channel activity
C	0005230	molecular_function	extracellular ligand-gated monoatomic ion channel activity
C	0005515	molecular_function	protein binding
C	0006811	biological_process	monoatomic ion transport
C	0016020	cellular_component	membrane
C	0034220	biological_process	monoatomic ion transmembrane transport
C	0042802	molecular_function	identical protein binding
C	0046872	molecular_function	metal ion binding
D	0004888	molecular_function	transmembrane signaling receptor activity
D	0005216	molecular_function	monoatomic ion channel activity
D	0005230	molecular_function	extracellular ligand-gated monoatomic ion channel activity
D	0005515	molecular_function	protein binding
D	0006811	biological_process	monoatomic ion transport
D	0016020	cellular_component	membrane
D	0034220	biological_process	monoatomic ion transmembrane transport
D	0042802	molecular_function	identical protein binding
D	0046872	molecular_function	metal ion binding
E	0004888	molecular_function	transmembrane signaling receptor activity
E	0005216	molecular_function	monoatomic ion channel activity
E	0005230	molecular_function	extracellular ligand-gated monoatomic ion channel activity
E	0005515	molecular_function	protein binding
E	0006811	biological_process	monoatomic ion transport
E	0016020	cellular_component	membrane
E	0034220	biological_process	monoatomic ion transmembrane transport
E	0042802	molecular_function	identical protein binding
E	0046872	molecular_function	metal ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	9
Details	BINDING SITE FOR RESIDUE SY9 A 1206

Chain	Residue
A	TYR91
A	TRP145
A	CYS188
A	TYR193
A	HOH2225
B	TYR53
B	GLN55
B	ILE116
B	SER165

---

site_id	AC2
Number of Residues	9
Details	BINDING SITE FOR RESIDUE SY9 B 1206

Chain	Residue
B	TYR91
B	SER144
B	TRP145
B	TYR186
B	CYS188
B	CYS189
B	TYR193
B	HOH2206
C	TYR53

---

site_id	AC3
Number of Residues	9
Details	BINDING SITE FOR RESIDUE SY9 C 1206

Chain	Residue
C	TYR91
C	SER144
C	TRP145
C	CYS188
C	TYR193
C	HOH2242
D	TYR53
D	ILE116
D	SER165

---

site_id	AC4
Number of Residues	10
Details	BINDING SITE FOR RESIDUE SY9 D 1206

Chain	Residue
D	TYR91
D	SER144
D	TRP145
D	TYR186
D	CYS188
D	TYR193
D	HOH2196
E	TYR53
E	ILE116
E	HOH2189

---

site_id	AC5
Number of Residues	8
Details	BINDING SITE FOR RESIDUE SY9 E 1206

Chain	Residue
A	TYR53
E	TYR91
E	SER144
E	TRP145
E	TYR186
E	TYR193
E	SY91207
E	HOH2229

---

site_id	AC6
Number of Residues	8
Details	BINDING SITE FOR RESIDUE SY9 E 1207

Chain	Residue
A	THR34
A	GLN55
A	ARG57
A	MET114
A	ILE116
A	ASP162
E	CYS188
E	SY91206

---