2XYT

Crystal structure of Aplysia californica AChBP in complex with d- tubocurarine

Summary for 2XYT

Related2WN9 2W8F 2BYP 2C9T 2BYQ 2W8G 2X00 2UZ6 2WNL 2BR7 2BR8 2XNV 2BYR 2BYN 2BYS 2XNT 2WNJ 2WZY 2WNC 2XNU 2XYS 2Y7Y
DescriptorSOLUBLE ACETYLCHOLINE RECEPTOR, D-TUBOCURARINE (3 entities in total)
Functional Keywordsreceptor, amidation, conformational flexibility, conotoxin, neurotoxin nicotinic, postsynaptic neurotoxin, receptor-toxin complex
Biological sourceAPLYSIA CALIFORNICA (CALIFORNIA SEA HARE)
Total number of polymer chains10
Total molecular weight249939.48
Authors
Brams, M.,Pandya, A.,Kuzmin, D.,van Elk, R.,Krijnen, L.,Yakel, J.L.,Tsetlin, V.,Smit, A.B.,Ulens, C. (deposition date: 2010-11-19, release date: 2011-03-23, Last modification date: 2011-12-28)
Primary citation
Brams, M.,Pandya, A.,Kuzmin, D.,Van Elk, R.,Krijnen, L.,Yakel, J.L.,Tsetlin, V.,Smit, A.B.,Ulens, C.
A Structural and Mutagenic Blueprint for Molecular Recognition of Strychnine and D-Tubocurarine by Different Cys-Loop Receptors.
Plos Biol., 9:1034-, 2011
PubMed: 21468359 (PDB entries with the same primary citation)
DOI: 10.1371/JOURNAL.PBIO.1001034
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.05 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.2176 0.2% 0.6% 2.2%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation reportDownload
169963
PDB entries from 2020-10-14