Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

2XYT

Crystal structure of Aplysia californica AChBP in complex with d- tubocurarine

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004888	molecular_function	transmembrane signaling receptor activity
A	0005216	molecular_function	monoatomic ion channel activity
A	0005230	molecular_function	extracellular ligand-gated monoatomic ion channel activity
A	0005515	molecular_function	protein binding
A	0006811	biological_process	monoatomic ion transport
A	0016020	cellular_component	membrane
A	0034220	biological_process	monoatomic ion transmembrane transport
A	0042802	molecular_function	identical protein binding
A	0046872	molecular_function	metal ion binding
B	0004888	molecular_function	transmembrane signaling receptor activity
B	0005216	molecular_function	monoatomic ion channel activity
B	0005230	molecular_function	extracellular ligand-gated monoatomic ion channel activity
B	0005515	molecular_function	protein binding
B	0006811	biological_process	monoatomic ion transport
B	0016020	cellular_component	membrane
B	0034220	biological_process	monoatomic ion transmembrane transport
B	0042802	molecular_function	identical protein binding
B	0046872	molecular_function	metal ion binding
C	0004888	molecular_function	transmembrane signaling receptor activity
C	0005216	molecular_function	monoatomic ion channel activity
C	0005230	molecular_function	extracellular ligand-gated monoatomic ion channel activity
C	0005515	molecular_function	protein binding
C	0006811	biological_process	monoatomic ion transport
C	0016020	cellular_component	membrane
C	0034220	biological_process	monoatomic ion transmembrane transport
C	0042802	molecular_function	identical protein binding
C	0046872	molecular_function	metal ion binding
D	0004888	molecular_function	transmembrane signaling receptor activity
D	0005216	molecular_function	monoatomic ion channel activity
D	0005230	molecular_function	extracellular ligand-gated monoatomic ion channel activity
D	0005515	molecular_function	protein binding
D	0006811	biological_process	monoatomic ion transport
D	0016020	cellular_component	membrane
D	0034220	biological_process	monoatomic ion transmembrane transport
D	0042802	molecular_function	identical protein binding
D	0046872	molecular_function	metal ion binding
E	0004888	molecular_function	transmembrane signaling receptor activity
E	0005216	molecular_function	monoatomic ion channel activity
E	0005230	molecular_function	extracellular ligand-gated monoatomic ion channel activity
E	0005515	molecular_function	protein binding
E	0006811	biological_process	monoatomic ion transport
E	0016020	cellular_component	membrane
E	0034220	biological_process	monoatomic ion transmembrane transport
E	0042802	molecular_function	identical protein binding
E	0046872	molecular_function	metal ion binding
F	0004888	molecular_function	transmembrane signaling receptor activity
F	0005216	molecular_function	monoatomic ion channel activity
F	0005230	molecular_function	extracellular ligand-gated monoatomic ion channel activity
F	0005515	molecular_function	protein binding
F	0006811	biological_process	monoatomic ion transport
F	0016020	cellular_component	membrane
F	0034220	biological_process	monoatomic ion transmembrane transport
F	0042802	molecular_function	identical protein binding
F	0046872	molecular_function	metal ion binding
G	0004888	molecular_function	transmembrane signaling receptor activity
G	0005216	molecular_function	monoatomic ion channel activity
G	0005230	molecular_function	extracellular ligand-gated monoatomic ion channel activity
G	0005515	molecular_function	protein binding
G	0006811	biological_process	monoatomic ion transport
G	0016020	cellular_component	membrane
G	0034220	biological_process	monoatomic ion transmembrane transport
G	0042802	molecular_function	identical protein binding
G	0046872	molecular_function	metal ion binding
H	0004888	molecular_function	transmembrane signaling receptor activity
H	0005216	molecular_function	monoatomic ion channel activity
H	0005230	molecular_function	extracellular ligand-gated monoatomic ion channel activity
H	0005515	molecular_function	protein binding
H	0006811	biological_process	monoatomic ion transport
H	0016020	cellular_component	membrane
H	0034220	biological_process	monoatomic ion transmembrane transport
H	0042802	molecular_function	identical protein binding
H	0046872	molecular_function	metal ion binding
I	0004888	molecular_function	transmembrane signaling receptor activity
I	0005216	molecular_function	monoatomic ion channel activity
I	0005230	molecular_function	extracellular ligand-gated monoatomic ion channel activity
I	0005515	molecular_function	protein binding
I	0006811	biological_process	monoatomic ion transport
I	0016020	cellular_component	membrane
I	0034220	biological_process	monoatomic ion transmembrane transport
I	0042802	molecular_function	identical protein binding
I	0046872	molecular_function	metal ion binding
J	0004888	molecular_function	transmembrane signaling receptor activity
J	0005216	molecular_function	monoatomic ion channel activity
J	0005230	molecular_function	extracellular ligand-gated monoatomic ion channel activity
J	0005515	molecular_function	protein binding
J	0006811	biological_process	monoatomic ion transport
J	0016020	cellular_component	membrane
J	0034220	biological_process	monoatomic ion transmembrane transport
J	0042802	molecular_function	identical protein binding
J	0046872	molecular_function	metal ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	17
Details	BINDING SITE FOR RESIDUE TC9 B 1206

Chain	Residue
B	TYR91
C	THR34
C	TYR53
C	GLN55
C	SER164
C	SER165
C	TYR166
G	SER187
G	HOH2188
B	SER92
B	ALA139
B	LYS141
B	TRP145
B	TYR186
B	HOH2117
B	HOH2169
B	HOH2170

site_id	AC2
Number of Residues	12
Details	BINDING SITE FOR RESIDUE TC9 D 1206

Chain	Residue
D	TRP145
D	TYR186
D	CYS188
D	CYS189
D	GLU191
D	TYR193
E	THR34
E	TYR53
E	GLN55
E	ARG57
E	MET114
E	SER165

site_id	AC3
Number of Residues	11
Details	BINDING SITE FOR RESIDUE TC9 F 1206

Chain	Residue
F	TYR91
F	LYS141
F	TRP145
F	TYR186
F	CYS188
F	CYS189
F	TYR193
F	HOH2135
G	TYR53
G	MET114
G	ILE116

site_id	AC4
Number of Residues	11
Details	BINDING SITE FOR RESIDUE TC9 G 1206

Chain	Residue
G	TRP145
G	TYR186
G	CYS189
G	GLU191
G	TYR193
G	HOH2191
G	HOH2197
H	THR34
H	GLN55
H	MET114
H	SER165

site_id	AC5
Number of Residues	12
Details	BINDING SITE FOR RESIDUE TC9 H 1206

Chain	Residue
H	TYR91
H	TRP145
H	TYR186
H	CYS189
H	TYR193
H	HOH2202
H	HOH2213
H	HOH2214
I	THR34
I	GLN55
I	MET114
I	SER165

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)
		EDMap 2fo-fc (MTZ)