3PXE
Impact of BRCA1 BRCT domain missense substitutions on phospho-peptide recognition: E1836K
Summary for 3PXE
Entry DOI | 10.2210/pdb3pxe/pdb |
Related | 1N5O 1T15 1T2U 1T2V 2ING 3PXA 3PXB 3PXC 3PXD |
Descriptor | Breast cancer type 1 susceptibility protein, phospho peptide (3 entities in total) |
Functional Keywords | brca1 protein, missense, protein binding, phosphopeptide recognition, brct domain, phospho-peptide binding, nuclear protein |
Biological source | Homo sapiens (human) More |
Cellular location | Nucleus . Isoform 3: Cytoplasm. Isoform 5: Cytoplasm : P38398 |
Total number of polymer chains | 8 |
Total formula weight | 102950.00 |
Authors | Coquelle, N.,Green, R.,Glover, J.N.M. (deposition date: 2010-12-09, release date: 2011-04-20, Last modification date: 2023-09-13) |
Primary citation | Coquelle, N.,Green, R.,Glover, J.N. Impact of BRCA1 BRCT Domain Missense Substitutions on Phosphopeptide Recognition. Biochemistry, 50:4579-4589, 2011 Cited by PubMed: 21473589DOI: 10.1021/bi2003795 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.85 Å) |
Structure validation
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