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3PXD

Impact of BRCA1 BRCT domain missense substitutions on phospho-peptide recognition: R1835P

Summary for 3PXD
Entry DOI10.2210/pdb3pxd/pdb
Related1N5O 1T15 1T2U 1T2V 2ING 3PXA 3PXB 3PXC 3PXE
DescriptorBreast cancer type 1 susceptibility protein, SULFATE ION, NICKEL (II) ION, ... (4 entities in total)
Functional Keywordsbrca1 protein, missense, phosphopeptide recognition, brct tandem repeats, phospho-peptide binding, nuclear protein, protein binding
Biological sourceHomo sapiens (human)
Cellular locationNucleus . Isoform 3: Cytoplasm. Isoform 5: Cytoplasm : P38398
Total number of polymer chains1
Total formula weight24625.91
Authors
Coquelle, N.,Green, R.,Glover, J.N.M. (deposition date: 2010-12-09, release date: 2011-04-20, Last modification date: 2023-09-13)
Primary citationCoquelle, N.,Green, R.,Glover, J.N.
Impact of BRCA1 BRCT Domain Missense Substitutions on Phosphopeptide Recognition.
Biochemistry, 50:4579-4589, 2011
Cited by
PubMed: 21473589
DOI: 10.1021/bi2003795
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.8 Å)
Structure validation

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