3PXC
Impact of BRCA1 BRCT domain missense substitutions on phospho-peptide recognition: R1699Q
Summary for 3PXC
Entry DOI | 10.2210/pdb3pxc/pdb |
Related | 1N5O 1T15 1T2U 1T2V 2ING 3PXA 3PXB 3PXD 3PXE |
Descriptor | Breast cancer type 1 susceptibility protein, SULFATE ION, NICKEL (II) ION, ... (4 entities in total) |
Functional Keywords | brca1 protein, missense, phosphopeptide recognition, brct tandem repeats, bach1 ctip abraxas, nuclear protein, protein binding |
Biological source | Homo sapiens (human) |
Cellular location | Nucleus . Isoform 3: Cytoplasm. Isoform 5: Cytoplasm : P38398 |
Total number of polymer chains | 1 |
Total formula weight | 24656.93 |
Authors | Coquelle, N.,Green, R.,Glover, J.N.M. (deposition date: 2010-12-09, release date: 2011-04-20, Last modification date: 2023-09-13) |
Primary citation | Coquelle, N.,Green, R.,Glover, J.N. Impact of BRCA1 BRCT Domain Missense Substitutions on Phosphopeptide Recognition. Biochemistry, 50:4579-4589, 2011 Cited by PubMed: 21473589DOI: 10.1021/bi2003795 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.8 Å) |
Structure validation
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