3PXE
Impact of BRCA1 BRCT domain missense substitutions on phospho-peptide recognition: E1836K
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Breast cancer type 1 susceptibility protein | polymer | 214 | 24531.3 | 4 | UniProt (P38398) Pfam (PF00533) | Homo sapiens (human) | RING finger protein 53 |
| 2 | E, F, G, H (E, F, G, H) | phospho peptide | polymer | 10 | 1206.2 | 4 | |||
| 3 | I, J, K, L (A, B, E, F) | water | water | 18.0 | 16 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 1646 - 1859 (UniProt: P38398)
| PDB | External Database | Details |
|---|---|---|
| Lys 1836 | Glu 1836 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 102950.0 | |
| All* | Total formula weight | 102950.0 |
