3PSC

Bovine GRK2 in complex with Gbetagamma subunits

3PSC の概要

• エントリーDOI: 10.2210/pdb3psc/pdb
• 関連するPDBエントリー: 1OMW 3CIK 3KRW 3KRX 3PVU 3PVW
• 分子名称: Beta-adrenergic receptor kinase 1, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... (4 entities in total)
• 機能のキーワード: kinase, serine/threonine-protein kinase, atp-binding, membrane, transferase-signaling protein complex, transferase/signaling protein
• 由来する生物種: Bos taurus (bovine); 詳細
• 細胞内の位置: Cell membrane; Lipid-anchor; Cytoplasmic side (Potential): P63212
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 126402.41

構造登録者

Thal, D.M.,Tesmer, J.J. (登録日: 2010-12-01, 公開日: 2011-06-01, 最終更新日: 2023-09-06)

• 主引用文献: Thal, D.M.,Yeow, R.Y.,Schoenau, C.,Huber, J.,Tesmer, J.J.; Molecular Mechanism of Selectivity among G Protein-Coupled Receptor Kinase 2 Inhibitors.; Mol.Pharmacol., 80:294-303, 2011; PubMed: 21596927; DOI: 10.1124/mol.111.071522

実験手法

X-RAY DIFFRACTION (2.67 Å)