3PSC
Bovine GRK2 in complex with Gbetagamma subunits
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Beta-adrenergic receptor kinase 1 | polymer | 695 | 80578.8 | 1 | UniProt (P21146) Pfam (PF00615) Pfam (PF00069) Pfam (PF00169) In PDB | Bos taurus (bovine) | GRK2, Beta-ARK-1, G-protein-coupled receptor kinase 2 |
2 | B | Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 | polymer | 340 | 37416.9 | 1 | UniProt (P62871) Pfam (PF00400) In PDB | Bos taurus (bovine) | Transducin beta chain 1 |
3 | G | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 | polymer | 74 | 8406.7 | 1 | UniProt (P63212) Pfam (PF00631) In PDB | Bos taurus (bovine) | G gamma-I |
4 | water | water | 18.0 | 8 | Chemie (HOH) |
Sequence modifications
A: 1 - 689 (UniProt: P21146)
G: 1 - 68 (UniProt: P63212)
PDB | External Database | Details |
---|---|---|
Ala 670 | Ser 670 | engineered mutation |
His 690 | - | expression tag |
His 691 | - | expression tag |
His 692 | - | expression tag |
His 693 | - | expression tag |
His 694 | - | expression tag |
His 695 | - | expression tag |
PDB | External Database | Details |
---|---|---|
His -5 | - | expression tag |
His -4 | - | expression tag |
His -3 | - | expression tag |
His -2 | - | expression tag |
His -1 | - | expression tag |
His 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 3 |
Total formula weight | 126402.4 | |
All* | Total formula weight | 126402.4 |