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3KBU

Crystal structure of the ankyrin binding domain of human erythroid beta spectrin (repeats 13-15) in complex with the spectrin binding domain of human erythroid ankyrin (ZU5-ANK), EMTS derivative

Summary for 3KBU
Entry DOI10.2210/pdb3kbu/pdb
Related1U4Q 3EDU 3EDV 3F57 3F59 3KBT
DescriptorSpectrin beta chain, erythrocyte, Ankyrin-1, MERCURY (II) ION (3 entities in total)
Functional Keywordscomplex, spectrin, spectrin repeat, three helix bundle, ankyrin binding, disease mutation, structural protein, ankyrin, zu5, beta sandwich, spectrin binding, cytoskeleton, membrane skeleton, actin capping, actin-binding, elliptocytosis, hereditary hemolytic anemia, phosphoprotein, alternative promoter usage, ank repeat, lipoprotein, membrane, sarcoplasmic reticulum
Biological sourceHomo sapiens (human)
More
Cellular locationCytoplasm, cytoskeleton: P11277
Isoform Er1: Cytoplasm, cytoskeleton. Isoform Mu17: Membrane. Isoform Mu18: Sarcoplasmic reticulum . Isoform Mu19: Sarcoplasmic reticulum . Isoform Mu20: Sarcoplasmic reticulum : P16157
Total number of polymer chains4
Total formula weight111814.61
Authors
Ipsaro, J.J.,Mondragon, A. (deposition date: 2009-10-20, release date: 2010-02-02, Last modification date: 2023-09-06)
Primary citationIpsaro, J.J.,Mondragon, A.
Structural basis for spectrin recognition by ankyrin.
Blood, 115:4093-4101, 2010
Cited by
PubMed: 20101027
DOI: 10.1182/blood-2009-11-255604
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.75 Å)
Structure validation

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