3F59
Crystal structure of ZU5-ANK, the spectrin binding region of human erythroid ankyrin
Summary for 3F59
| Entry DOI | 10.2210/pdb3f59/pdb |
| Related | 3F57 |
| Descriptor | Ankyrin-1, BROMIDE ION (3 entities in total) |
| Functional Keywords | beta sandwich, zu5, ankyrin, spectrin binding, alternative promoter usage, ank repeat, cytoskeleton, disease mutation, elliptocytosis, hereditary hemolytic anemia, lipoprotein, membrane, phosphoprotein, sarcoplasmic reticulum, structural protein |
| Biological source | Homo sapiens |
| Cellular location | Isoform Er1: Cytoplasm, cytoskeleton. Isoform Mu17: Membrane. Isoform Mu18: Sarcoplasmic reticulum . Isoform Mu19: Sarcoplasmic reticulum . Isoform Mu20: Sarcoplasmic reticulum : P16157 |
| Total number of polymer chains | 4 |
| Total formula weight | 72980.65 |
| Authors | Ipsaro, J.J.,Huang, L.,Mondragon, A. (deposition date: 2008-11-03, release date: 2009-02-24, Last modification date: 2023-12-27) |
| Primary citation | Ipsaro, J.J.,Huang, L.,Mondragon, A. Structures of the spectrin-ankyrin interaction binding domains. Blood, 113:5385-5393, 2009 Cited by PubMed: 19141864DOI: 10.1182/blood-2008-10-184358 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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