3KBU

Crystal structure of the ankyrin binding domain of human erythroid beta spectrin (repeats 13-15) in complex with the spectrin binding domain of human erythroid ankyrin (ZU5-ANK), EMTS derivative

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Spectrin beta chain, erythrocyte	polymer	326	37219.4	2	UniProt (P11277) Pfam (PF00435) In PDB	Homo sapiens (human)	Beta-I spectrin
2	C, D	Ankyrin-1	polymer	161	17885.6	2	UniProt (P16157) Pfam (PF00791) In PDB	Homo sapiens (human)	Erythrocyte ankyrin, Ankyrin-R
3	A, B, C, D	MERCURY (II) ION	non-polymer		200.6	8	Chemie (HG)

Sequence modifications

A, B: 1583 - 1906 (UniProt: P11277)

PDB	External Database	Details
Ser 1581	-	expression tag
Asn 1582	-	expression tag
Cys 1680	Glu 1680	engineered mutation
Asp 1844	Glu 1844	SEE REMARK 999
Val 1845	Leu 1845	SEE REMARK 999

C, D: 911 - 1068 (UniProt: P16157)

PDB	External Database	Details
Ser 908	-	expression tag
Asn 909	-	expression tag
Ala 910	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	110209.9
Non-Polymers*	Number of molecules	8
	Total formula weight	1604.7
All*	Total formula weight	111814.6

*Water molecules are not included.