2Y61
Crystal structure of Leishmanial E65Q-TIM complexed with S-Glycidol phosphate
Summary for 2Y61
Entry DOI | 10.2210/pdb2y61/pdb |
Related | 1AMK 1IF2 1N55 1QDS 2VXN 2Y62 2Y63 |
Descriptor | TRIOSEPHOSPHATE ISOMERASE SYNONYM TRIOSE-PHOSPHATE ISOMERASE, TIM, SN-GLYCEROL-1-PHOSPHATE, SN-GLYCEROL-3-PHOSPHATE, ... (5 entities in total) |
Functional Keywords | isomerase, fatty acid biosynthesis, transition state analogue, glycolysis, pentose shunt, gluconeogenesis, enzyme-ligand complex |
Biological source | LEISHMANIA MEXICANA |
Total number of polymer chains | 1 |
Total formula weight | 27736.57 |
Authors | Venkatesan, R.,Alahuhta, M.,Pihko, P.M.,Wierenga, R.K. (deposition date: 2011-01-19, release date: 2011-12-14, Last modification date: 2023-12-20) |
Primary citation | Venkatesan, R.,Alahuhta, M.,Pihko, P.M.,Wierenga, R.K. High resolution crystal structures of triosephosphate isomerase complexed with its suicide inhibitors: the conformational flexibility of the catalytic glutamate in its closed, liganded active site. Protein Sci., 20:1387-1397, 2011 Cited by PubMed: 21633986DOI: 10.1002/pro.667 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (0.99 Å) |
Structure validation
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