2VXN
E65Q-TIM complexed with phosphoglycolohydroxamate at 0.82 A resolution
Summary for 2VXN
| Entry DOI | 10.2210/pdb2vxn/pdb |
| Related | 1AMK 1IF2 1N55 1QDS |
| Descriptor | TRIOSEPHOSPHATE ISOMERASE, PHOSPHOGLYCOLOHYDROXAMIC ACID, 2-PHOSPHOGLYCOLIC ACID, ... (6 entities in total) |
| Functional Keywords | isomerase, fatty acid biosynthesis, transition state analogue, glycolysis, pentose shunt, gluconeogenesis, tim, glycosome, triosephosphate isomerase, enzyme-ligand complex, lipid synthesis, transition state, protonation state |
| Biological source | LEISHMANIA MEXICANA |
| Total number of polymer chains | 1 |
| Total formula weight | 28054.83 |
| Authors | Alahuhta, M.,Wierenga, R.K. (deposition date: 2008-07-08, release date: 2009-07-14, Last modification date: 2023-12-13) |
| Primary citation | Alahuhta, M.,Wierenga, R.K. Atomic Resolution Crystallography of a Complex of Triosephosphate Isomerase with a Reaction-Intermediate Analog: New Insight in the Proton Transfer Reaction Mechanism. Proteins, 78:1878-, 2010 Cited by PubMed: 20235230DOI: 10.1002/PROT.22701 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (0.82 Å) |
Structure validation
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