Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004807 | molecular_function | triose-phosphate isomerase activity |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005829 | cellular_component | cytosol |
| A | 0006094 | biological_process | gluconeogenesis |
| A | 0006096 | biological_process | glycolytic process |
| A | 0016853 | molecular_function | isomerase activity |
| A | 0019563 | biological_process | glycerol catabolic process |
| A | 0020015 | cellular_component | glycosome |
| A | 0046166 | biological_process | glyceraldehyde-3-phosphate biosynthetic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 16 |
| Details | BINDING SITE FOR RESIDUE PGH A 1251 |
| Chain | Residue |
| A | ASN11 |
| A | LEU232 |
| A | GLY234 |
| A | GLY235 |
| A | HOH2402 |
| A | HOH2403 |
| A | HOH2404 |
| A | HOH2405 |
| A | LYS13 |
| A | HIS95 |
| A | GLU167 |
| A | ALA171 |
| A | ILE172 |
| A | GLY173 |
| A | GLY212 |
| A | SER213 |
| site_id | AC2 |
| Number of Residues | 16 |
| Details | BINDING SITE FOR RESIDUE PGA A 1252 |
| Chain | Residue |
| A | ASN11 |
| A | LYS13 |
| A | HIS95 |
| A | GLU167 |
| A | ALA171 |
| A | ILE172 |
| A | GLY173 |
| A | GLY212 |
| A | SER213 |
| A | LEU232 |
| A | GLY234 |
| A | GLY235 |
| A | HOH2402 |
| A | HOH2403 |
| A | HOH2404 |
| A | HOH2405 |
| site_id | AC3 |
| Number of Residues | 15 |
| Details | BINDING SITE FOR RESIDUE GOL A 1253 |
| Chain | Residue |
| A | PHE45 |
| A | PHE45 |
| A | ASN66 |
| A | ASN66 |
| A | GLY76 |
| A | GLY76 |
| A | GLU77 |
| A | GLU77 |
| A | ARG98 |
| A | HOH2193 |
| A | HOH2193 |
| A | HOH2406 |
| A | HOH2406 |
| A | HOH2407 |
| A | HOH2407 |
| site_id | AC4 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE GOL A 1254 |
| Chain | Residue |
| A | HIS89 |
| A | GLY120 |
| A | MET122 |
| A | ASN197 |
| A | GOL1255 |
| A | HOH2292 |
| A | HOH2408 |
| site_id | AC5 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE GOL A 1255 |
| Chain | Residue |
| A | GLY120 |
| A | LEU144 |
| A | SER145 |
| A | SER148 |
| A | TRP193 |
| A | GOL1254 |
| A | HOH2409 |
| A | HOH2410 |
| A | HOH2412 |
| site_id | AC6 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE GOL A 1256 |
| Chain | Residue |
| A | GLU30 |
| A | HIS31 |
| A | THR32 |
| A | GLY175 |
| A | HOH2325 |
| A | HOH2413 |
| A | HOH2414 |
| A | HOH2415 |
| site_id | AC7 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE GOL A 1257 |
| Chain | Residue |
| A | LEU24 |
| A | THR179 |
| A | GLU181 |
| A | PRO240 |
| A | HOH2416 |
| A | HOH2417 |
| A | HOH2418 |
| site_id | AC8 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE ACT A 1258 |
| Chain | Residue |
| A | TRP170 |
| A | GLN182 |
| A | PRO240 |
| A | GLU241 |
| A | ARG243 |
| A | ASP244 |
| A | HOH2272 |
| A | HOH2419 |
Functional Information from PROSITE/UniProt
| site_id | PS00171 |
| Number of Residues | 11 |
| Details | TIM_1 Triosephosphate isomerase active site. AYEPVWAIGTG |
| Chain | Residue | Details |
| A | ALA165-GLY175 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | Active site: {"description":"Electrophile"} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | Active site: {"description":"Proton acceptor"} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | Binding site: {} |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 5 |
| Details | Annotated By Reference To The Literature 1hti |
| Chain | Residue | Details |
| A | LYS13 | |
| A | HIS95 | |
| A | ASN11 | |
| A | GLU167 | |
| A | GLY173 | |
