2Y48

Crystal structure of LSD1-CoREST in complex with a N-terminal SNAIL peptide

Summary for 2Y48

• Entry DOI: 10.2210/pdb2y48/pdb
• Related: 2COM 2H94 2IW5 2UXN 2UXX 2V1D 2X0L 2XAF 2XAG 2XAH 2XAJ 2XAQ 2XAS
• Descriptor: LYSINE-SPECIFIC DEMETHYLASE 1A, REST COREPRESSOR 1, ZINC FINGER PROTEIN SNAI1, ... (4 entities in total)
• Functional Keywords: oxidoreductase, flavin, histone, repressor, transcription regulation, chromatin, nuclear protein
• Biological source: HOMO SAPIENS (HUMAN); More
• Cellular location: Nucleus: O60341 Q9UKL0 O95863
• Total number of polymer chains: 3
• Total formula weight: 104702.50

Authors

Baron, R.,Binda, C.,Tortorici, M.,McCammon, J.A.,Mattevi, A. (deposition date: 2011-01-05, release date: 2011-02-16, Last modification date: 2023-12-20)

• Primary citation: Baron, R.,Binda, C.,Tortorici, M.,Mccammon, J.A.,Mattevi, A.; Molecular Mimicry and Ligand Recognition in Binding and Catalysis by the Histone Demethylase Lsd1-Corest Complex.; Structure, 19:212-, 2011; PubMed: 21300290; DOI: 10.1016/J.STR.2011.01.001

Experimental method

X-RAY DIFFRACTION (3 Å)